Post chemo possibilites Updated 2/1/18 4:30pm


January 16, 2018  12:00pm                       Back to In the Beginning


Starting to look in to what's next after chemo and just so I know where to find these articles when the time comes; I thought I'd put them in here.

FDA checkpoint - bladder cancer therapies

The rapid uptake of immunotherapy in bladder cancer

Cancer types/bladder cancer

Astrazeneca:FDA approves bladder cancer drug


Proton therapy

Immunotherapy treatment center in CA


Immunotherapy possibilities (mostly post-chemo therapies if cancer comes back)

Oncolytic virus therapy

Enadenotrucirev in combination with Keytruda(pembrolizumab)

Checkpoint inhibitors/Immune Modulators

Ateolizumab for high risk muscle invasive bladder cancer after surgery or in combination with varlilumab

Durvalumab and tremelumumab and Poly-ICLC

Nivolumab + ipilimumab and cabosantinib

Adaptive Cell Therapy

Remove T cells, modify with chemicals to increase activity and reintroduce them to improve response

Monoclonal Antibodies

Ramucirumab, B-701, HuMax

Adjuvants

So far only for non-muscle invasive cancer


Other:

PD-L1 inhibitors

Imfinzi – also helps immune cells kill cancer

Durvalumab $15k/month, beswt if PD-L1 levels are high

Proton therapy?


Stem cell regrowth
https://youtu.be/OtL1fEEtLaA

Stem cell regrowth

Gene editing
CRISPR gene editing

CRISPR editing at UPenn

Vitamin C and cancer

Surgery

Neobladder

Support group

January 22, 2018 4:00pm
Thanks to all of you who have been concerned that there haven't been any updates.  Well in this case, no news is good news.  No fever, no hospitalization, no pain in the leg. Eating well, although Wednesday starts another round of fasting. I don't know whether to love or hate Steve Nicoletti for finding that study.  My good friend Matt D'Alessandro sent me some samples of his photography ..here's one of my favorites of a canyon near Page in AZ.




January 24, 2018 3:15pm
Started fasting again this morning.  Gave another couple vials of blood at the cancer center and this time the phlebotomist actually hit the target on the first attempt.  My veins have a lot of scar tissue right at the elbows from frequent blood donations, so they have to target a bit higher than normal to actually hit a part of the vein that will work.  Took about a half mile walk along the abandoned railroad spur out back at lunch time just to escape the food smells in the office. 


The lock on my nephrostomy tube has been stabbing me in the back right where the port goes in for two days depending on how I move or sit.  Very uncomfortable and will need to re-bandage it to try to avoid that. Can't wait to hear what the oncologist has in store for us on Friday since this is the last chemo treatment and he hasn't hinted at what's next.


Next: Fourth and Final....maybe

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